Table 4.
Unadjusted and adjusted logistic regression analyses for progression to severe aortic stenosis in total patients with calcific aortic valve disease.
| Univariable | Multivariable | |||
|---|---|---|---|---|
| OR (95% CI) | p value | OR (95% CI) | p value | |
| Follow-up durations, year | 1.67 (1.45–1.91) | < 0.001* | 1.63 (1.34–1.98) | < 0.001 |
| Age, year | 1.03 (1.00–1.07) | 0.074* | ||
| Male gender | 1.50 (0.81–2.76) | 0.194* | ||
| Body mass index, kg/m2 | 0.99 (0.93–1.06) | 0.764 | ||
| Smoking ever | 2.03 (0.95–4.35) | 0.067* | ||
| Hypertension | 1.13 (0.52–2.48) | 0.758 | ||
| Diabetes | 1.13 (0.60–2.13) | 0.698 | ||
| Dyslipidemia | 1.46 (0.75–2.83) | 0.267 | ||
| Coronary artery disease | 0.48 (0.21–1.10) | 0.082* | ||
| CRP, mg/dl | 0.96 (0.87–1.05) | 0.346 | ||
| LDL-C, per 25 mg/dl increase | 1.21 (1.01–1.45) | 0.034* | 1.23 (1.02–1.50) | 0.034 |
| Peak aortic jet velocity, per 0.5 m/s increase | 5.02 (3.62–6.95) | < 0.001* | 6.38 (4.12–9.89) | < 0.001 |
CRP, C-reactive protein; LDL, low-density lipoprotein cholesterol.
*
p value indicates the presence of statistical significance (p < 0.20).