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. 2023 Mar 2;30(10):960–968. doi: 10.1093/eurjpc/zwad066

Table 2.

Frequency of cardiorenal outcomes and mortality by sex, clinical comorbidities, and educational attainment

Overall Cardiovascular composite Coronary heart disease Heart failure Ischaemic stroke Haemorrhagic stroke Renal failure Death Cardiac death
n 48 721 7166 (14.7%) 5294 (10.9%) 3301 (6.8%) 2766 (5.7%) 582 (1.2%) 2677 (5.5%) 2763 (5.7%) 1388 (2.8%)
Female 25 315 (52.0%) 2984 (41.6%) 2003 (37.8%) 1288 (39.0%) 1211(43.8%) 272 (46.7%) 981 (36.6%) 971 (35.1%) 394 (28.4%)
Diabetes mellitus 10 616 (21.8%) 1399 (19.5%) 1130 (21.3%) 721 (21.8%) 547 (19.8%) 83 (14.3%) 849 (31.7%) 726 (26.3%) 424 (30.5%)
Obesity 4160 (8.5%) 274 (3.8%) 201 (3.8%) 159 (4.8%) 111 (4.0%) 18 (3.1%) 170 (6.4%) 149 (5.4%) 89 (6.4%)
Hypercholesterolaemia 16 425 (33.7%) 1908 (26.6%) 1544 (29.2%) 893 (27.1%) 756 (27.3%) 141 (24.2%) 920 (34.4%) 783 (28.3%) 451 (32.5%)
Alcohol abuse 5094 (10.5%) 861 (12.0%) 618 (11.7%) 519 (15.7%) 387 (14.0%) 82 (14.1%) 485 (18.1%) 645 (23.3%) 342 (24.6%)
Smokinga 14 893 (52.7%) 2486 (55.4%) 1895 (58.3%) 1289 (60.6%) 1008 (53.8%) 208 (55.9%) 961 (58.2%) 1334 (66.9%) 715 (68.8%)
Educational attainmentb
 Secondary 19 610 (53.8%) 2569 (56.4%) 1921 (57.4%) 1178 (59.1%) 986 (56.8%) 196 (55.5%) 970 (56.2%) 981 (62.6%) 463 (64.1%)
 Post-secondary 8721 (23.9%) 1057 (23.2%) 782 (23.4%) 463 (23.2%) 392 (22.6%) 76 (21.5%) 380 (22.0%) 323 (20.6%) 138 (19.1%)
 Higher 8122 (22.3%) 929 (20.4%) 641 (19.2%) 351 (17.6%) 359 (20.7%) 81 (22.9%) 375 (21.7%) 264 (16.8%) 121 (16.8%)

Proportions based on n = 28 286 individuals for whom smoking data was available.

Proportions based on n = 36 453 individuals for whom educational attainment data was available.