Table 2.
Levels of inflammatory and OS biomarkers according to the presence of MS components.
| Hypertension | No (N=35) | Yes (N=83) | p |
|---|---|---|---|
| IL-6 (pg/mL), median (IQR) | 2.1 (2.6) | 2.5 (1.8) | 0.278 |
| TNF-α (pg/mL), median (IQR) | 1.0 (0.4) | 1.1 (0.4) | 0.002 |
| Leptin (ng/mL), median (IQR) | 37.4 (32.1) | 34.8 (39.2) | 0.859 |
| Adiponectin (μg/mL), median (IQR) | 5.6 (6.7) | 5.9 (9.6) | 0.950 |
| oxLDL (U/l), median (IQR) | 79.2 (28.8) | 70.0 (43.5) | 0.177 |
| oxLDL/LDL (U/mmoL), median (IQR) | 22.0 (9.8) | 27.1 (11.5) | 0.001 |
| oxLDL/HDL (U/mmoL), median (IQR) | 54.7 (44.7) | 61.7 (35.4) | 0.165 |
| MPO (ng/mL), median (IQR) | 91.1 (155.0) | 72.2 (114.2) | 0.870 |
| CRP (mg/L), median (IQR) | 2.3 (4.7) | 2.3 (4.0) | 0.711 |
| Hyperglycemia | No (N=79) | Yes (N=42) | p |
| IL-6 (pg/mL), median (IQR) | 2.2 (1.6) | 3.1 (3.0) | 0.069 |
| TNF-α (pg/mL), median (IQR) | 1.0 (0.3) | 1.2 (0.5) | 0.017 |
| Leptin (ng/mL), median (IQR) | 36.9 (34.2) | 33.1 (45.3) | 0.408 |
| Adiponectin (μg/mL), median (IQR) | 6.3 (9.2) | 4.1 (5.7) | 0.101 |
| oxLDL (U/l), median (IQR) | 77.4 (29.1) | 82.1 (38.9) | 0.264 |
| oxLDL/LDL (U/mmoL), median (IQR) | 24.2 (8.8) | 30.0 (12.6) | 0.001 |
| oxLDL/HDL (U/mmoL), median (IQR) | 57.9 (30.4) | 67.4 (43.1) | 0.091 |
| MPO (ng/mL), median (IQR) | 85.9 (133.7) | 77.9 (145.2) | 0.455 |
| CRP (mg/L), median (IQR) | 2.4 (3.6) | 1.9 (5.7) | 0.752 |
| Hyperlipidemia | No (N=14) | Yes (N=108) | p |
| IL-6 (pg/mL), median (IQR) | 1.7 (4.2) | 2.4 (1.6) | 0.615 |
| TNF-α (pg/mL), median (IQR) | 1.0 (0.3) | 1.1 (0.4) | 0.158 |
| Leptin (ng/mL), median (IQR) | 39.4 (74.5) | 34.8 (34.8) | 0.163 |
| Adiponectin (μg/mL), median (IQR) | 5.1 (7.0) | 6.2 (8.2) | 0.527 |
| oxLDL (U/l), median (IQR) | 74.2 (41.4) | 77.9 (32.9) | 0.629 |
| oxLDL/LDL (U/mmoL), median (IQR) | 26.9 (8.1) | 25.6 (10.4) | 0.401 |
| oxLDL/HDL (U/mmoL), median (IQR) | 54.9 (24.5) | 62.9 (39.8) | 0.271 |
| MPO (ng/mL), median (IQR) | 109.8 (137.9) | 79.2 (146.8) | 0.724 |
| CRP (mg/L), median (IQR) | 4.3 (6.0) | 2.3 (3.6) | 0.317 |
Data are expressed as median (interquartile range, IQR). MS, metabolic syndrome; IL-6, interleukin-6; TNF-α, tumor necrosis factor-α; oxLDL, oxidized low-density lipoprotein; HDL, high-density lipoprotein; LDL, low-density lipoprotein; MPO, myeloperoxidase; CRP, C-reactive protein. Comparisons between groups were performed by the Mann–Whitney U test. Level of significance was set as 0.05. Significant p are in bold.