Fig. 2.

Mechanism of action between CAP and biofilm. At low-doses of CAP, a the outer structure of biofilm is slightly damaged, b QS signaling molecules are not significantly affected, c persisters are induced to form in biofilms, and d ROS is restricted in the biofilm surface. At high-dose of CAP, e the outer structure of biofilm is seriously damaged, f QS signaling molecules are destroyed, g the bacterial structure in the biofilm is seriously damaged, and h ROS diffuses to the deep layer of biofilm. Green spots represent ROS and RNS in the CAP. Purple triangles represent QS signaling molecules. Gray ellipses represent bacteria in biofilm. Green ellipses represent persister cells