Fig. 2.

PK profile simulations of BAM + ETE. PK profile simulations of BAM + ETE were conducted in a simulation dataset of 518 virtual participants weighing ≤ 12 kg, weights ranging from 3.2 to 12 kg, and ages ranging from 0.5 to 53 months. Datasets display 90% prediction intervals for BAM (top) and ETE (bottom) and concentration-time profiles in pediatric participants weighing ≤ 12 kg following administration of 12/24 mg/kg BAM + ETE (left panels) and 15/30 mg/kg BAM + ETE (right panels) compared with exposures in adult participants at the authorized dose of 700 mg/1400 mg BAM + ETE