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. 2023 Jul 31;13:12395. doi: 10.1038/s41598-023-38904-1

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Visualization of correlation matrix of sumatriptan with genes known to be involved in cAMP regulation, i.e., GNAI1 and VIPR2. Above the diagonal the absolute value of the correlation with significance (**p < 0.01, ***p < 0.001), on the diagonal histograms of the change in expression of VIPR2, GNAI1 and sumatriptan, and below the diagonal the bivariate scatterplots. Note that values on both y- and x-axis are change in levels/expression after treatment with sumatriptan.