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. 2023 Jul 31;14:4494. doi: 10.1038/s41467-023-40201-4

Fig. 4. Untargeted lipidomic analysis of free fatty acids and lysophospholipids released in TAC-operated Pla2g6−/− heart tissue.

Fig. 4

a Heat map showing the contents of molecular species of free fatty acids and lysophospholipids in mouse hearts after TAC operation. Correlation of peak values and color is indicated at the top; High, red and low, blue. Red arrow indicates 18:0 lysophosphatidylserine. LPS lysophosphatidylserine, LPI lysophosphatidylinositol, LPG lysophosphatidylglucoside, LPE lysophosphatidylethanolamine, LPC lysophosphatidylcholine, FA free fatty acid. b Quantity of 18:0 lysophosphatidylserine in mouse hearts after TAC operation. n = 4 (sham-operated Pla2g6+/+), 4 (sham-operated Pla2g6–/–), 5 (TAC-operated Pla2g6+/+), and 5 (TAC-operated Pla2g6–/–), biologically independent samples. Average values of each group were used for heat map analysis (a). Open and closed bars indicate Pla2g6+/+ and Pla2g6−/−, respectively (b). Data are expressed as the mean ± SEM. The data were evaluated by one-way ANOVA, followed by Tukey-Kramer’s post-hoc test. Source data are provided as a Source Data file.