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. 2023 Aug 1;14(8):488. doi: 10.1038/s41419-023-06009-2

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — A Apoptosis statistics in indicated cell lines with different HK2 and AIMP2 status after 8 Gy radiation, respectively (n = 3). B Western blotting of apoptosis-related protein including Cyto c, Caspase/Cleaved Caspase 3 in indicated groups post 8 Gy radiation. C Subcutaneous xenograft nude mice model to twice 8 Gy radiation responsiveness among human HCC cells with different HK2 and AIMP2 status in MHCC97H. Tumor growth rate and images upon necropsy were presented. D Representative IHC staining of Ki-67 and Cyto c in the formalin-fixed tumor sections from indicated groups, Scale bar 20 μm. Data were represented as mean ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.