Table 7.
Multinomial logistic regression reporting the RRR and 95% CI for the association of different variables with the coexistence of frailty, sarcopenia, cognitive impairment, and anorexia of aging.
| Variables | None of criterion existed | One criterion vs. None of criterion | Two criteria vs. None criterion | Three criteria vs. None criterion | Four criteria vs. None criterion | |
|---|---|---|---|---|---|---|
| Age | Reference group | 1.09 (1.06–1.11) | 1.15 (1.12–1.18) | 1.21 (1.16–1.25) | 1.22 (1.12–1.33) | |
| Sex | Reference group | 0.46 (0.36–0.59) | 0.34 (0.25–0.47) | 0.36 (0.20–0.64) | 0.36 (0.08–1.65) | |
| Low physical activity | Reference group | 1.93 (1.26–2.94) | 2.55 (1.62–4.01) | 15.57 (7.86–30.83) | 98.11 (8.97–1072.75) | |
| Cancer | Reference group | 1.08 (0.40–2.97) | 1.64 (0.57–4.69) | 0.91 (0.20–4.14) | NA | |
| MNA score | Reference group | 0.80 (0.74–0.86) | 0.67 (0.61–0.73) | 0.57 (0.51–0.64) | 0.39 (0.31–0.49) | |
| PHQ-9 score | Reference group | 0.86 (0.72–1.03) | 1.05 (0.85–1.30) | 1.48 (1.11–1.97) | 1.66 (0.92–3.01) | |
| Waist circumference | Reference group | 1.02 (1.01–1.04) | 1.03 (1.01–1.05) | 1.06 (1.02–1.10) | 1.05 (0.95–1.16) | |
| BMI | Reference group | 0.93 (0.89–0.97) | 0.81 (0.76–0.85) | 0.82 (0.74–0.91) | 0.94 (0.70–1.26) | |
| Smoking | Reference group | 1.15 (0.89–1.50) | 1.09 (0.78–1.52) | 0.96 (0.55–1.70) | 1.24 (0.30–5.09) | |
| WBC | Reference group | 1.00 (0.95–1.05) | 0.98 (0.92–1.04) | 1.00 (0.91–1.10) | 1.03 (0.78–1.36) | |
| Alcohol consumption | Reference group | 1.42 (0.61–3.30) | 0.34 (0.06–1.85) | NA | NA | |
| Single | Reference group | 1 | 1 | 1 | 1 | |
| Marital status | Married | Reference group | 1.14 (0.33–3.92) | 1.18 (0.24–5.79) | 1.16 (0.09–14.69) | NA |
| Divorced | Reference group | 0.53 (0.10–2.72) | 0.66 (0.09–5.10) | NA | NA | |
| Widow | Reference group | 1.20 (0.34–4.21) | 1.24 (0.25–6.20) | 1.05 (0.08–13.59) | NA | |
| No drug consumed | Reference group | 1 | 1 | 1 | 1 | |
| Number of drugs | 1–4 drugs consumed | Reference group | 0.98 (0.71–1.34) | 0.73 (0.48–1.10) | 0.58 (0.28–1.21) | 0.20 (0.03–1.46) |
| 5 drugs or more consumed (Polypharmacy) | Reference group | 0.84 (0.62–1.13) | 0.67 (0.46–0.98) | 0.56 (0.29–1.07) | 0.27 (0.06–1.28) | |
NA: could not be assessed by the model. Age, sex, cancer, physical activity, number of drugs, marital status, BMI, waist circumference, WBC, smoking, MNA score, PHQ-9 score, and alcohol consumption were entered into the model. Log likelihood = − 2350.773, Pseudo R2 = 0.1876.