Reduction of CoQ10 and DCPIP with rat liver homogenate or isolated fractions. (A) HPLC chromatograms of reaction mixtures containing CoQ10 (200 μM), NADH (2.0 mM), and rat liver homogenate at 0 min (upper) and 60 min (lower) during incubation at 37°C. (B) Time course of DCPIP reduction with rat liver homogenate (■) or isolated fraction 1 (□), 2 (△), 3 (◇), 4 (○), and 5 (×). (C) Time course of CoQ10 reduction with rat liver homogenate (■) or isolated fraction 1 (□), 2 (△), 3 (◇), 4 (○), and 5 (×). (D) Time course of CoQ10 reduction in the absence of NADH with rat liver homogenate (■) or isolated fraction 1 (□), 2 (△), 3 (◇), 4 (○), and 5 (×).