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. 2023 Jul 25;642:123139. doi: 10.1016/j.ijpharm.2023.123139

Table 2.

Composition of buffer solutions.

Composition Gastric fluid
Intestinal fluid
pH 1.6 pH 3.0 pH 5.0 pH 5.8 pH 6.5
Hydrochloric acid (mM) 25.1
Ortho-phosphoric acid (mM) 5.5
Monobasic sodium phosphate (mM) 32 133.8 28.4
Sodium hydroxide (mM) 3.1 82 8.7
Maleic acid (mM) 55
pH (adjusted by HCl 0.1 N or NaOH 0.1 N) 1.6 3.0 5.0 5.8 6.5