Table 3.
Nine genes associated with neutrophil degranulation that had significantly increased mRNA levels in patients with Prolonged MODS/Died compared to Recovered MODS.
| Gene | Gene Full Name/Alias | Log2 fold change | P value | FDR adjusted P value* |
References |
|---|---|---|---|---|---|
| RETN | Resistin, Cysteine-Rich Protein Precursor 1 | 777.914 | 9.51E-08 | 0.00005 | (8, 15, 16) |
| TCN1 | Haptocorin, Transcobalamin 1, Vitamin B12 Binding Protein, R Binder Family | 613.987 | 4.48E-07 | 0.0001 | (8, 15) |
| OLFM4 | Olfactomedin 4, 2’-5’-Oligoadenylate Synthetase 2, G-CSF-Stimulated Clone 1 Protein, GC1 | 923.158 | 5.36E-06 | 0.0008 | |
| LCN2 | Lipocalin 2, Neutrophil Gelatinase-Associated Lipocalin, 25 KDa Alpha-2-Microglobulin-Related Subunit Of MMP-9 | 2048.845 | 6.29E-06 | 0.0008 | |
| BPI | Bactericidal Permeability Increasing Protein, B Cell CLL/Lymphoma 3 | 377.357 | 1.41E-05 | 0.001 | |
| MMP8 | Matrix Metallopeptidase 8, Neutrophil Collagenase | 2621.675 | 3.13E-05 | 0.002 | |
| LTF | Lactotransferrin, Neutrophil Lactoferrin | 569.083 | 0.000111134 | 0.005 | (15, 17) |
| S100A12 | S100 Calcium Binding Protein A12, Calgranulin-C, ENRAGE | 38819.741 | 0.000426456 | 0.02 | (18) |
| GUSB | Glucuronidase Beta | 66.579 | 0.000427102 | 0.02 | (15, 19) |
*q value.