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. 2023 May 17;22(8):913–925. doi: 10.1158/1535-7163.MCT-22-0743

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©2023 The Authors; Published by the American Association for Cancer Research

This open access article is distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) license.

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Figure 5. Antitumor efficacy of 9MW2821 in CDXs. A–C, TGI evaluated in MDA-MB-468, NCI-H322M, HT1376 xenograft models. Xenograft mice (n = 8) were intravenously treated with 1, 3, or 10 mg/kg 9MW2821 or EV at 3 mg/kg or 10 mg/kg for one injection. All treatments were initiated on the day when the average tumor volume reached 100 to 150 mm3. The tumor inhibition rates are mean values of eight animals. — Antitumor efficacy of 9MW2821 in CDXs. A–C, TGI evaluated in MDA-MB-468, NCI-H322M, HT1376 xenograft models. Xenograft mice (n = 8) were intravenously treated with 1, 3, or 10 mg/kg 9MW2821 or EV at 3 mg/kg or 10 mg/kg for one injection. All treatments were initiated on the day when the average tumor volume reached 100 to 150 mm³. The tumor inhibition rates are mean values of eight animals.