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. 2023 Jun 26;42(15):e111247. doi: 10.15252/embj.2022111247

Figure EV5. Excitatory synapses are reduced in the hippocampal neurons in CD38 AS‐cKOP10 mice.

Figure EV5

  • A–D
    (A, C) Immunohistochemistry for VGlut1 (green) and PSD95 (magenta) in the stratum radiatum of the CA1 (A) and CA2 (C) of ctrlP10 and CD38 AS‐cKOP10 mice at P70. The VGlut1 and PSD95 channels are separated in the middle panels. Right panels are colocalized VGlut1 and PSD95 puncta. Scale bar, 10 μm. (B, D) Quantification synapses (colocalization of VGlut1 and PSD95) in each area of the hippocampus (n = 4 animals per genotype, two‐tailed unpaired Student's t‐test).

Data information: Data represent means ± SEM. *P < 0.05.