TABLE 3.
Odds Ratio of Health Care Utilization Associated with Complete Medication Initiations by Different Adjustment Models
| Concurrent Analysis | Prospective Analysis | |||||
|---|---|---|---|---|---|---|
| Any IP (95% CI) | Any ED (95% CI) | Top 5% Users (95% CI) | Any IP (95% CI) | Any ED (95% CI) | Top 5% Users (95% CI) | |
| Model 1: Complete initiation + number of orders | 0.597a (0.530, 0.672) | 0.739a (0.695, 0.786) | 0.663a (0.605, 0.727) | 0.999 (0.897, 1.112) | 0.979 (0.918, 1.045) | 0.903b (0.828, 0.985) |
| Model 2: Complete initiation + number of orders + PS weighting | 0.770a (0.674, 0.880) | 0.775a (0.727, 0.826) | 0.778a (0.703, 0.861) | 0.977 (0.871, 1.095) | 0.926b (0.866, 0.990) | 0.884a (0.806, 0.970) |
| Model 3: Complete initiation + number of orders + age + sex + DxRx PM score | 0.592a (0.523, 0.670) | 0.698a (0.656, 0.743) | 0.651a (0.586, 0.724) | 1.012 (0.908, 1.128) | 0.949 (0.888, 1.013) | 0.927 (0.845, 1.018) |
| Model 4: Complete initiation + number of orders + age + sex + DxRx PM score + PS weighting | 0.783a (0.680, 0.902) | 0.766a (0.717, 0.818) | 0.766a (0.679, 0.864) | 1.001 (0.892, 1.125) | 0.928b (0.868, 0.993) | 0.908 (0.822, 1.004) |
Note: DxRx PM score = a score based on a predictive model derived from the Johns Hopkins ACG System using diagnoses and NDC numbers found in the claims. Number of orders = number of first-ordered e-prescriptions derived from the EHR during the year.
a P < 0.01.
b P < 0.05.
ACG = Adjusted Clinical Group; CI = confidence interval; ED = emergency department; EHR = electronic health record; IP = inpatient; NDC =National Drug Code; PS = propensity score.