TABLE 4.

Odds Ratio of Polypharmacy for Young and Middle-Aged Adults with CP Only and CP + NDDs Compared with Elderly Adults Without CP

	> 5 Medications	> 10 Medications	>15 Medications
	OR (95% CI)	OR (95% CI)	OR (95% CI)
Elderly, ≥ 65 years, without CP	Reference	Reference	Reference
Young, 18-40 years
CP only
Unadjusted	0.51 (0.46-0.57)	0.53 (0.46-0.61)	0.54 (0.44-0.67)
Model 1	1.03 (0.93-1.15)	1.46 (1.26-1.69)	2.01 (1.59-2.54)
CP +NDDs
Unadjusted	1.09 (0.97-1.23)	1.06 (0.94-1.21)	1.16 (0.98-1.39)
Model 1	2.09 (1.84-2.38)	2.57 (2.22-2.97)	3.27 (2.66-4.02)
Middle age, 41-64 years
CP only
Unadjusted	1.21 (1.12-1.32)	1.30 (1.19-1.41)	1.66 (1.49-1.85)
Model 1	1.55 (1.41-1.70)	1.85 (1.68-2.05)	2.60 (2.29-2.96)
CP + NDDs
Unadjusted	1.58 (1.37-1.82)	1.78 (1.56-2.03)	2.24 (1.92-2.62)
Model 1	1.99 (1.71-2.32)	2.43 (2.09-2.83)	3.11 (2.58-3.75)

Note: Model 1: sex, U.S. region of residence, and multimorbidity.

CI = confidence interval; CP = cerebral palsy; NDD = neurodevelopmental disabilities; OR = odds ratio.