TABLE 4.
Adherence to Oral TKIs Among Patients in FIHPs and SFHPs Before and After Parity
| FIHPs | SFHPs | Unadjusted DD | Adjusted DD | |||||
|---|---|---|---|---|---|---|---|---|
| Before parity | After parity | Before parity | After parity | DD | 95% CI | aDD | 95% CI | |
| Overall, N | 480 | 198 | 688 | 521 | – | – | – | – |
| PDC, median (Q1, Q3) | 0.96 (0.79, 1.00) | 0.98 (0.89, 1.00) | 0.98 (0.83, 1.00) | 0.98 (0.89, 1.00) | – | – | – | – |
| PDC, mean (SD) | 0.85 (0.22) | 0.87 (0.20) | 0.87 (0.21) | 0.90 (0.17) | −0.01 | (−0.03-0.01) | −0.01 | (−0.03-0.01) |
| PDC ≥ 0.80 (%) | 74.2% | 78.2% | 78.9% | 84.4% | 0.96 | (0.85-1.09) | 0.97 | (0.86-1.10) |
| PDC ≥ 0.85 (%) | 69.2% | 73.2% | 73.6% | 78.3% | 0.94 | (0.82-1.09) | 1.00 | (0.90-1.13) |
| PDC ≥ 0.90 (%) | 63.1% | 66.2% | 67.7% | 72.5% | 0.95 | (0.85-1.06) | 0.93 | (0.84-1.04) |
| With limit, n | 204 | 53 | 350 | 110 | – | – | – | – |
| PDC, median (Q1, Q3) | 0.96 (0.80, 1.00) | 0.98 (0.86, 1.00) | 0.98 (0.83, 1.00) | 0.98 (0.87, 1.00) | – | – | – | – |
| PDC, mean (SD) | 0.85 (0.22) | 0.90 (0.16) | 0.88 (0.20) | 0.90 (0.17) | 0.02 | (−0.01-0.06) | 0.02 | (−0.01-0.06) |
| PDC ≥ 0.80 (%) | 75.0% | 81.1% | 79.7% | 83.6% | 1.02 | (0.81-1.30) | 1.02 | (0.80-1.31) |
| PDC ≥ 0.85 (%) | 69.6% | 75.5% | 73.1% | 78.2% | 1.01 | (0.81-1.25) | 1.05 | (0.84-1.31) |
| PDC ≥ 0.90 (%) | 62.3% | 71.7% | 67.4% | 70.0% | 1.08 | (0.88-1.32) | 1.10 | (0.89-1.36) |
| Without limit, n | 276 | 145 | 338 | 411 | – | – | – | – |
| PDC, median (Q1, Q3) | 0.96 (0.78, 1.00) | 0.95 (0.83, 1.00) | 0.98 (0.83, 1.00) | 0.98 (0.90, 1.00) | – | – | – | – |
| PDC, mean (SD) | 0.85 (0.22) | 0.86 (0.21) | 0.87 (0.22) | 0.90 (0.17) | −0.03 | (−0.06-0.00) | −0.03 | −0.05-0.00) |
| PDC ≥ 0.80 (%) | 73.5% | 77.2% | 78.1% | 84.7% | 0.94 | (0.81-1.10) | 0.96 | (0.83-1.11) |
| PDC ≥ 0.85 (%) | 68.8% | 72.4% | 74.0% | 78.4% | 0.98 | (0.86-1.13) | 1.00 | (0.87-1.15) |
| PDC ≥ 0.90 (%) | 63.8% | 64.1% | 68.1% | 75.9% | 0.91 | (0.80-1.04) | 0.90 | (0.79-1.02) |
Notes: Linear regression was used for estimating mean absolute changes in PDC. Logistic regression odds ratios are represented to estimate the probability of achieving levels of adherence based on various PDC (ie, ≥ 0.80, ≥ 0.85, ≥ 0.90).
aDD = adjusted difference-in-differences; DD = difference-in-differences; FIHP = fully insured health plan; PDC = proportion of days covered; SFHP = self-funded health plan.