TABLE 1.
Patient Demographics and Baseline Clinical Characteristics
| 2018 adult AD cohort (n=31,164) | 2018 adult control cohorta (n=93,492) | |
|---|---|---|
| Age, mean years (SD) | 45.3 (16.8) | 45.3 (16.8) |
| Sex, n (%) | ||
| Female | 20,037 (64.3) | 60,111 (64.3) |
| Male | 11,127 (35.7) | 33,381 (35.7) |
| Geographic region, n (%) | ||
| Northeast | 9,447 (30.3) | 28,341 (30.3) |
| North Central | 4,396 (14.1) | 13,188 (14.1) |
| South | 12,782 (41.0) | 38,346 (41.0) |
| West | 4,539 (14.6) | 13,617 (14.6) |
| Medicare (vs commercial), n (%) | 2,977 (9.6) | 8,887 (9.5) |
| Deyo-Charlson Comorbidity Index, mean (SD) | 0.7 (1.3) | 0.5 (1.2)b |
| Comorbid medical conditions, n (%) | ||
| Allergies | 11,619 (37.3) | 14,006 (15.0)b |
| Anxiety | 5,568 (17.9) | 13,678 (14.6)b |
| Asthma | 5,345 (17.2) | 7,010 (7.5)b |
| Cardiovascular disease | 10,465 (33.6) | 28,441 (30.4)b |
| Depression | 4,732 (15.2) | 11,538 (12.3)b |
| Pain | 19,937 (64.0) | 50,511 (54.0)b |
| Pruritus | 3,754 (12.1) | 2,233 (2.4)b |
| Skin infections | 10,431 (33.5) | 16,230 (17.4)b |
| Sleep disorders | 4,662 (15.0) | 10,690 (11.4)b |
| Incident AD (vs prevalent) c | 25,868 (83.0) | NA |
aControls were directly matched to AD patients (3:1) on age, sex, and geographic region.
bP < 0.001.
cPatients without any claims with an AD diagnosis in the 24 months before the index date were considered to have incident AD.
AD = atopic dermatitis; NA = not available.