TABLE 2.
All-Cause and Atopic Dermatitis-Related Health Care Utilization Among Adult Patients in the 2018 Cohort
| All cause | AD relateda | |||
|---|---|---|---|---|
| Adult AD cohort (n=31,164) | Adult control cohort (n = 93,492) | Incremental difference | Adult AD cohort (n = 31,164) | |
| Inpatient admissions | ||||
| Patients with an admission, n (%) | 1,680 (5.4) | 4,996 (5.3) | 0.05% | 56 (0.2) |
| Number of admissions,b mean (SD) | 1.2 (0.7) | 1.3 (0.7) | − 0.02 | 1.0 (0.0) |
| Length of stay in days,c mean (SD) | 3.8 (4.0) | 3.8 (4.8) | − 0.05 | 5.3 (5.2) |
| Outpatient services | ||||
| Patients with an ED visit, n (%) | 6,664 (21.4) | 16,462 (17.6)e | 3.8% | 70 (0.2) |
| Number of ED visits,d mean (SD) | 0.4 (0.9) | 0.3 (0.8)e | 0.1 | 0.0 (0.1) |
| Patients with an outpatient office visit, n (%) | 31,124 (99.9) | 78,740 (84.2)e | 15.7% | 30,600 (98.2) |
| Number of outpatient office visits,d mean (SD) | 9.1 (7.5) | 4.8 (5.7)e | 4.3 | 1.6 (1.4) |
| Patients with other outpatient services, n (%) | 29,998 (96.3) | 79,141 (84.7)e | 11.6% | 12,320 (39.5) |
| Number of other outpatient services,d mean (SD) | 15.4 (19.1) | 9.2 (14.6)e | 6.2 | 0.8 (3.5) |
| Patients with a phototherapy service, n (%) | 608 (2.0) | 48 (0.1)e | 1.9% | 464 (1.5) |
| Number of phototherapy servicesd, mean (SD) | 0.4 (4.1) | 0.01 (0.7)e | 0.4 | 0.2 (3.2) |
| Outpatient pharmacy services | ||||
| Patients with an outpatient prescription, n (%) | 30,261 (97.1) | 75,840 (81.1)e | 16.0% | 28,479 (91.4) |
| Number of prescriptions,d mean (SD) | 21.3 (21.7) | 14.0 (18.9)e | 723.6% | 5.5 (5.7) |
| AD patients with a prescription for AD-related medications, n (%) | ||||
| Systemic medications | ||||
| Antibiotics | 4,222 (13.5) | |||
| Antihistamines | 4,883 (15.7) | |||
| Antivirals | 4,116 (13.2) | |||
| Oral corticosteroids | 13,424 (43.1) | |||
| Dupilumab | 1,989 (6.4) | |||
| Immunosuppressants | 406 (1.3) | |||
| Topical medications | ||||
| Antibiotics | 17,627 (56.6) | |||
| Calcineurin inhibitors | 2,992 (9.6) | |||
| Corticosteroids | 22,138 (71.0) | |||
| PDE-4 inhibitors | 2,402 (7.7) | |||
a AD claims were defined as medical claims with a diagnosis of AD and outpatient pharmacy claims for corticosteroids, antibiotics, calcineurin inhibitors, antivirals, dupilumab, immunosuppressants, or phosphodiesterase-4 inhibitors. A list of generic names of drugs is included in Supplementary Table 1 (59.5KB, pdf) .
b Among patients with at least 1 admission.
c Per admission.
d Among all patients.
e P < 0.001, AD cohort vs control cohort.
AD = atopic dermatitis.