TABLE 3.
Medication Complexity and Adherence Indices by Age, Sex, Chronic Conditions, and Inpatient Visits (2012)
| EHRs | Claims | Both | ||||
|---|---|---|---|---|---|---|
| ICD Count | Rx Count | MRCI | MPR (%) | Charlson Comorbidity Index | PFR (30 days, %) | |
| Age, years (mean ± SD)a | ||||||
| < 18 | 10.3 ± 11.4 | 2.6 ± 2.1 | 10.8 ± 12.6 | 46.9 ± 35.9 | 0.151 ± 0.404 | 89.2 ± 23.7 |
| 18-29 | 10.8 ± 13.8 | 3.3 ± 2.9 | 11.66 ± 14.0 | 66.0 ± 34.1 | 0.152 ± 0.448 | 79.6 ± 28.7 |
| 30-49 | 13.6 ± 19.8 | 3.9 ± 4.3 | 14.1 ± 20.9 | 62.1 ± 26.1 | 0.253 ± 1.029 | 80.2 ± 26.4 |
| 50-64 | 18.6 ± 15.4 | 5.1 ± 3.5 | 18.5 ± 17.3 | 65.7 ± 32.0 | 0.506 ± 0.694 | 78.8 ± 27.7 |
| Sex (mean ± SD)a | ||||||
| Male | 12.5 ± 14.7 | 3.7 ± 3.2 | 13.7 ± 16.4 | 62.0 ± 32.6b | 0.332 ± 0.817 | 82.7 ± 26.5 |
| Female | 15.6 ± 17.7 | 4.3 ± 3.9 | 15.3 ± 18.6 | 62.6 ± 30.1 | 0.292 ± 0.751 | 80.0 ± 27.2 |
| Chronic condition (mean ± SD)a | ||||||
| No | 6.4 ± 6.4 | 2.0 ± 1.3 | 6.2 ± 6.6 | 60.5 ± 39.2 | 0.053 ± 0.302 | 87.5 ± 26.6 |
| Yes | 16.4 ± 17.8 | 4.5 ± 3.9 | 16.9 ± 19.1 | 62.6 ± 29.7 | 0.375 ± .849 | 79.7 ± 26.9 |
| Inpatient visit (mean ± SD)a | ||||||
| No | 13.4 ± 14.4 | 3.9 ± 3.4 | 13.9 ± 16.4 | 63.0 ± 31.1 | 0.271 ± 0.691 | 81.3 ± 27.1 |
| Yes | 36.3 ± 37.9 | 8.0 ± 6.4 | 33.2 ± 33.0 | 50.3 ± 27.6 | 1.204 ± 1.696 | 75.7 ± 23.6 |
aAnalysis of variance or t-tests were performed to evaluate the difference of variance for ICD count, prescription count, MRCI, and Charlson Comorbidity Index score in subcategories. The nonparametric Kruskal-Wallis test was performed for MPR and PFR.
bAll within-group comparisons had significantly different medication indices at P < 0.001 except MPR in male and female patients.
ICD = International Classification of Diseases; MPR = medication possession ratio; MRCI = medication regimen complexity index; PFR = prescription fill rate; Rx = prescription; SD = standard deviation.