FIG. 5.

Putative amino acid sequences of the Rep ORFs. The Rep ORFs of AAV2, AAV3A, AAV3B, AAV4, AAV6, and AAV5 were compared by using the MACAW alignment program. Identical amino acids are shown with white letters on a black background. Dashes indicate gaps in the sequence added by the alignment program. The putative ATP-binding site (ATP) and Zn fingers (three pairs of black dots above the sequences for all AAVs except AAV5, and two pairs of black triangles below the sequences for AAV5) are marked. ×, start of the two unspliced Rep proteins.