TABLE 1.

Percentage of identical amino acids in the right-sided (“cap”) ORF derived from AAV alignments^a

AAV serotype alignments	% Identical amino acids
	Pairwise		Group
	Aligned to AAV4	Aligned to AAV5
Pairwise
AAV2	61.5	58.3
AAV3A	63.9	58.4
AAV3B	64.8	58.7
AAV4	100	51.4
AAV6	64.6	58.8
Group
AAV2, AAV3A, AAV3B, and AAV6			80.1
AAV2, AAV3A, AAV3B, and AAV6 versus AAV4			59.7
AAV2, AAV3A, AAV3B, and AAV6 versus AAV5			53.2
AAV2, AAV3A, AAV3B, and AAV6 versus AAV4 and AAV5			44.9

^aThe right-sided AAV ORFs were aligned either pairwise or in the indicated combinations with the MACAW program, and the identical amino acids were determined.