Table 2.
Clinical characteristics of patients with sarcopenia and nonsarcopenia according to the EWGSOP2 guidelines.
| NDD-CKD | MHD | |||||
|---|---|---|---|---|---|---|
| Sarcopenia (n = 6) |
Nonsarcopenia (n = 99) |
P | Sarcopenia (n = 39) |
Nonsarcopenia (n = 86) |
P | |
| Age (years) | 52.70 ± 18.7 | 52.07 ± 10.33 | 0.944 | 66.82 ± 11.69 | 56.01 ± 14.99 | <0.001* |
| Males [n(%)] | 3 (50.0) | 49 (49.5) | 0.981 | 23 (59.0) | 45 (52.3) | 0.489 |
| BMI (kg/m2) | 20.1 ± 1.1 | 24.8 ± 3.2 | <0.001* | 20.4 ± 2.9 | 22.7 ± 3.8 | 0.001* |
| Comorbidities [n(%)] | ||||||
| Hypertension | 2 (33.3) | 64 (64.6) | 0.123 | 35 (89.7) | 74 (86.0) | 0.566 |
| Diabetes | 1 (16.7) | 18 (18.2) | 0.925 | 14 (35.9) | 18 (20.9) | 0.076 |
| Cardiovascular disease | 0 (0) | 8 (8.1) | 0.469 | 19 (48.7) | 30 (34.9) | 0.142 |
| Dialysis vintage (months) | / | / | / | 76.9 ± 69.2 | 65.8 ± 52.3 | 0.375 |
| SARC-F score | 2 (1, 3.75) | 0 (0, 0) | <0.001* | 3 (1, 5) | 0 (0, 2) | <0.001* |
| ASM (kg) | 14.79 ± 4.16 | 18.90 ± 4.14 | 0.020* | 14.51 ± 3.08 | 17.93 ± 4.17 | <0.001* |
| ASMI (kg/m2) | 5.41 ± 0.85 | 6.78 ± 1.00 | 0.001* | 5.41 ± 0.87 | 6.56 ± 1.07 | <0.001* |
| HGS (kg) | 16.8 ± 4.1 | 32.5 ± 10.9 | <0.001* | 13.6 ± 6.9 | 26.6 ± 10.4 | <0.001* |
| Chair stand (s) | 13.5 (12.5, 15.1) | 9.8 (7.3, 11.0) | <0.001* | 13.7 (12.0, 19.1) | 10.2 (7.9, 12.3) | <0.001* |
| Gait speed (m/s) | 1.06 (0.89, 1.18) | 1.12 (1.03, 1.25) | 0.139 | 0.80 (0.46, 1.02) | 1.02 (0.86, 1.19) | <0.001* |
*P < 0.05.
CKD-NDD, chronic kidney disease with nondialysis dependence; MHD, maintenance hemodialysis; BMI, body mass index; HGS, handgrip strength; ASM, appendicular skeletal muscle mass; ASMI, appendicular skeletal muscle mass index.