Table 1.

Comparison of RT-LAMP assay in saliva purified RNA vs. raw saliva diagnosed with an individual primer set.

RT-PCR			RT-LAMP
Total (n)	Positive (n)	Negative (n)	Primer set	Sensitivity (%) 95% CI	Specificity (%) 95% CI	PPV (%) 95% CI	NPV (%) 95% CI	Accuracy (%) 95% CI
Nasopharyngeal Swab			Saliva Purified RNA
61	32	29	ORF1a-HMS	87.5 (71.0‒96.4)	93.1 (77.1‒99.9)	93.3 (77.9‒99.1)	87.1 (70.2‒96.3)	90.1 (79.8‒96.3)
96	56	37	Gene E	75 (61.9‒85.6)	97.3 (85.8‒99.9)	97.7 (87.7‒99.9)	72.0 (57.5‒83.7)	83.87 (74.8‒90.6)
52	39	13	Gene N-A	58.9 (42.1‒74.4	92.3 (63.9‒99.8)	95.8 (78.8‒99.8)	42.8 (24.7‒62.8)	67.31 (52.8‒79.6)
Nasopharyngeal Swab			Raw Saliva
42	22	22	ORF1a-HMS	81.8 (59.7‒98.4)	90.9 (70.8‒98.8)	90.0 (68.3‒98.7)	83.3 (62.6‒95.2)	86.3 (72.6‒94.8)
44	52	38	Gene E	71.1 (56.9‒82.3)	97.37 (86.1‒99.3)	97.4 (86.1‒99.3)	71.7 (56.9‒82.8	80.43 (70.9‒88.0)
43	34	11	Gene N-A	47.0 (29.7‒64.8)	100.0 (100‒100)	100 (79.4‒100)	37.9 (20.6‒57.7)	50.0 (36.0‒63.9)