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. Author manuscript; available in PMC: 2023 Dec 15.
Published in final edited form as: J Affect Disord. 2022 Oct 4;319:213–220. doi: 10.1016/j.jad.2022.09.155

Fig 3. DHNA prevented UCMS-induced depression-like behavior in female, but not male, mice.

Fig 3.

Male (A, C, E, G) and female (B, D, F, H) mice received vehicle or DHNA, and then were unstressed or subjected to UCMS for 4 weeks. Sucrose preference was monitored weekly starting at the end of the second week of UCMS, and continuing until 1 week post UCMS (A, B). Then mice were examined for FST (C, D), splash test (E, F), and tape groom test (G, H). (*)Bonferroni post hoc contrast indicates a significant difference from unstressed mice (p < 0.05); (§) Bonferroni post hoc contrast indicates a significant difference from DHNA/UCMS (p < 0.05). (ε)Bonferroni post hoc contrast indicates a significant difference from DHNA/NS (p < 0.05). Results are presented as mean + SEM.