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. Author manuscript; available in PMC: 2023 Dec 15.
Published in final edited form as: J Affect Disord. 2022 Oct 4;319:213–220. doi: 10.1016/j.jad.2022.09.155

Fig 4. DHNA prevented UCMS-induced stress-response in males.

Fig 4.

Male (A, C, E, G, I, K, M, O) and female (B, D, F, H, J, L, N, P) were examined for their baseline emotional state. Then, they received vehicle or DHNA, were unstressed or subjected to UCMS for 4 weeks, and retested. Data is presented as the difference between the re-test and baseline for novelty-induced locomotion (A, B); time spent in the center in the OFT (C, D); time spent in the light compartment in the L/D test (E, F); number of buried marbles (G, H); latency for the first sip in the NIH test in their home cages (I, J) and novel environment (K, L); and time spent in the open arm (M, N) and total crosses (O, P) in the EPM. (*) Bonferroni post hoc contrast indicates a significant difference from the other groups (p < 0.05). Results are presented as mean + SEM.