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. 2023 May 29;26(7):107006. doi: 10.1016/j.isci.2023.107006

Figure 4.

Figure 4

MET or SHP2 inhibitors revert MET-mediated resistance in vitro

The indicated tetON-MET cells were cultured with doxycycline for 24 h before they were treated with the indicated targeted therapies and combinations.

(A) The cell lines were analyzed in 6-day viability assays. Data are represented as mean of n = 3 ± SD.

(B) The cell lines were analyzed in two week colony formation assays.