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. 2023 Aug 1;23:204. doi: 10.1186/s12866-023-02935-5

Table 1.

Sensitivity and specificity for STTT in America and in Europe

Symptoms / Stage of the disease Patient's localization
America Europe
Sensitivitya Specificityb References Sensitivity Specificity References

Erythema migrans or early Lyme borreliosis

Acute phasec (AP)

11–50% 99% [29, 34, 5457] 23–55% 75–99% [34, 5861]

Erythema migrans or early Lyme borreliosis

Convalescent phased (CP)

18–78% 99% 30–67% 95% [61]
Acute-phase neurologic or cardiac involvement 60–100% 99% 69–97% 98–99% [58, 61]
Arthritis or late neurologic involvement 97–100% 99% 78–100% 98–99%

aAbility of the test to identify the presence of a disease correctly (CDC)

bAbility of the test to identify the absence of a disease correctly (CDC)

cPhase during an active infection, characterized by active multiplication of the pathogens and pronounced symptoms

dPhase after the antibiotic treatment