Table 4.
Differences in breastfeeding and non-breastfeeding mothers with SLE 6 months after delivery
| N |
Breastfeeding N = 44 |
N |
Non-breastfeeding N = 38 |
p-valuea | |
|---|---|---|---|---|---|
| Age ≥ 35 years, (%) | 44 | 18.2 | 38 | 36.8 | 0.08 |
| BMI (kg/m2), mean (SD) | 36 | 25.6 (5.6) | 26 | 24.3 (5.5) | 0.26 |
| Overweight (≥ 25 kg/m2) | 17 (47.2) | 9 (34.6) | 0.44 | ||
| Work status (full -or parttime), (%) | 39 | 7.7 | 27 | 11.1 | 0.68 |
| VAS scores (0–100), median (IQR) | 27 | 21 | |||
| Pain | 24 (8–40) | 20 (0–49) | 0.88 | ||
| Fatigue | 26 (3–50) | 30 (5- 63) | 0.62 | ||
| Global score | 12 (3–37) | 25 (8–55) | 0.23 | ||
| Inflammatory active diseaseb (%) | 36 | 5.6 | 23 | 4.3 | 1.00 |
| CRP value (mg/L), mean (SD) | 37 | 2.30 (2.2) | 26 | 2.7 (3.1) | 0.81 |
| Regular physical activityc (%) | 18 | 66.7 | 21 | 61.9 | 1.00 |
| Medications, n (%) | 44 | 38 | |||
| HCQ | 34 (77.3) | 28 (73.7) | 0.80 | ||
| sDMARDd | 16 (36.4) | 13 (34.2) | 1.00 | ||
| bDMARDe | 0 | 1 (2.6) | - |
SD standard deviation, BMI body mass index, CRP C-reactive protein, VAS visual analog scale, IQR interquartile range, HCQ hydroxychloroquine, sDMARDs synthetic disease modifying anti-rheumatic drugs, bDMARDs biologic disease modifying anti-rheumatic drugs
agroup comparisons were performed using Fisher´s exact test for categorical variables and independent samples t-test for continuous, normally distributed variables. For ordinal and continuous, non-normally distributed data Mann Whitney U test was performed
bmeasured by LAI-P/SLEDAI. Active disease: ≥ 2,2 (LAI-P) or > 6 (SLEDAI)
cat least once weekly
d sDMARDs included azathioprine, methotrexate, sulphasalazine and mycophenolate mofetil
ebDMARDs included belimumab, TNF-inhibitors and interleukin inhibitors