Perioperative glycaemic control for people with diabetes undergoing surgery

. 2023 Aug 1;2023(8):CD007315. doi: 10.1002/14651858.CD007315.pub3

Study ID	Intervention(s) and comparator(s)	Participants included in analysis (N)	Participants discontinuing trial due to an adverse event (N)	Participants discontinuing trial due to an adverse event (%)
Duncan 2018	I: hyperinsulinaemic normoglycaemia	226*	0*	0*
Duncan 2018	C: standard therapy	249*	0*	0*
Wallia 2017	I: intensive	23*	0*	0*
Wallia 2017	C: moderate	26*	0*	0*
Wahby 2016	I: tight glycaemic control	67	0	0
Wahby 2016	C: conventional moderate glycaemic control	68	0	0
Parekh 2016	I: moderately intense control	30	0	0
Parekh 2016	C: standard glucose control	30	0	0
Yuan 2015	I: intensive glycaemic management	106	0	0
Yuan 2015	C: conventional glycaemic management	106	0	0
Umpierrez 2015	I: intensive group	77^*	0^*	0^*
Umpierrez 2015	C: conservative control	75^*	0^*	0^*
Abdelmalak 2013	I: intensive glucose management	54*	0*	0*
Abdelmalak 2013	C: conventional glucose management	49*	0*	0*
Hermayer 2012	I: intensive glycaemic control	44	—	—
Hermayer 2012	C: standard glycaemic control	49	—	—
Desai 2012	I: strict blood glucose control	37*	—	—
Desai 2012	C: liberal blood glucose control	44*	—	—
Lazar 2011	I: aggressive glucose control	40	0	0
Lazar 2011	C: moderate glucose control	42	0	0
Cao 2010	I: intensive insulin therapy	92	—	—
Cao 2010	C: conventional insulin therapy	87	—	—
Glucontrol 2009	I: intensive insulin treatment	55*	—	—
Glucontrol 2009	C: intermediate glucose control	69*	—	—
NICE SUGAR 2009	I: intensive insulin therapy	3054^a	304^a	10^a
NICE SUGAR 2009	C: conventional insulin therapy	3050^a	225^a	7.4^a
Subramaniam 2009	I: continuous insulin infusion	62*	0*	0*
Subramaniam 2009	C: standard intermittent sliding‐scale insulin bolus	64*	0*	0*
Chan 2009	I: intensive insulin therapy	55^a	7^a	12.7^a
Chan 2009	C: conventional insulin therapy	54^a	4^a	7.4^a
De La Rosa 2008	I: intensive insulin therapy	254^a	0^a	0^a
De La Rosa 2008	C: conventional insulin therapy	250^a	0^a	0^a
Gandhi 2007	I: intensive insulin therapy	37	0	0
Gandhi 2007	C: conventional insulin therapy	36	0	0
Li 2006	I: continuous insulin infusion	51	—	—
Li 2006	C: glucometer‐guided insulin	42	—	—
Lazar 2004	I: tight glycaemic control with GIK	72	0	0
Lazar 2004	C: standard therapy	69	0	0
Rassias 1999	I: aggressive insulin therapy	13	0	0
Rassias 1999	C: standard insulin therapy	13	0	0
—: denotes not reported ^adata from total study population. data provided by study authors (patients with diabetes). C: comparator; I: intervention; GIK*: glucose‐insulin‐potassium.