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. 2023 Feb 9;56(8):e13419. doi: 10.1111/cpr.13419

FIGURE 1.

FIGURE 1

Benzyl butyl phthalate (BBP) exposure leads to a decrease in the number of oocyte and antral follicle, as well as the developmental potential of oocyte. (A) Representative images of the oocytes obtained from control and BBP‐exposed ovary after superovulation. (B) The number of oocytes obtained from BBP‐exposed (1.5 mg/kg body weight/day) group were significantly reduced comparing with control and BBP‐exposed (0.5 mg/kg body weight/day) groups. Results are expressed as mean ± SD; experiments were repeated at least three times (NS, not significant; *p < 0.05; **p < 0.01; *** p < 0.001). (C) Most oocytes obtained from BBP‐exposed group could only grow to MI stages, but most of control oocytes could reach to the MII phase. (D) Ovary weight was not changed after BBP exposure. Results are expressed as mean ± SD; experiments were repeated at least three times (NS, not significant; *p < 0.05; **p < 0.01; ***p < 0.001). (E) Average body weight was not changed after BBP exposure. (F) Pictures of control and BBP‐exposed ovary sections. (G) Number of antral follicles per ovary was significantly reduced in BBP‐exposed group than that in control. Results are expressed as mean ± SD; experiments were repeated at least three times (NS, not significant; *p < 0.05; **p < 0.01; ***p < 0.001).