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. Author manuscript; available in PMC: 2023 Aug 1.
Published in final edited form as: Compr Physiol. 2023 Jan 30;13(1):4295–4319. doi: 10.1002/cphy.c220010

Figure 3.

Figure 3

Inflammatory components in plexiform type lesions of PAH. Inflammatory cells are highlighted by the anti-CD45 immunostaining (arrowheads) (A), B-cell marker (UL-26) (B), T-cell marker (UCHSC) (C), and macrophage marker (CD68) (D and E) (arrowheads). Note infiltration of the outer portion of the plexogenic vessel (D) and vessel obliterated by concentric proliferation (E) by macrophages (immunoperoxidase, A-C, E 500X; D: 200x). I-Vascular lumen. Reused, with permission, from Tuder RM, et al., 1994 (199), from Elsevier.