Table 2.
Patients with Nocardia kroppenstedtii infection in the literature.
Case No. | References | Sex/age | Underlying disease | Immunosuppressive treatment for underlying disease | Systemic involvement of N. kroppenstedtii infection | Specimen(s) from which N. kroppenstedtii was isolated | Identification method | Antimicrobial treatment | Patient outcome |
---|---|---|---|---|---|---|---|---|---|
1 | Jones et al. (4) | Not mentioned | Lung transplant | Not mentioned | Not mentioned | BAL | 16S rDNA gene sequencing | Not mentioned | Not mentioned |
2 | Kilianski et al. (8) | M/72 | Mantle cell lymphoma | Bendamustine, rituximab, bortezomib, ibrutinib, methotrexate, and methylprednisolone | CNS, cardiovascular system | Blood | 16S rDNA gene sequencing | Meropenem, cotrimoxazole, levofloxacin, linezolid, ceftriaxone, minocycline, and ciprofloxacin | Succumbed |
3 | Majeed et al. (9) | F/59 | Lung carcinoma | Radiotherapy, carboplatin, and etoposide | Eye, brain | Blood | Gene sequencing | Vancomycin, piperacillin-tazobactam, meropenem, and intravitreal injection of amikacin | Succumbed |
4 | Venkat et al. (10) | F/78 | Autoimmune hemolytic anemia | Corticosteroid | Spine and spinal cord | Pus | 16S rDNA gene sequencing | Cloxacillin, cotrimoxazole, and carbapenem | Improved |
5 | Present case | F/71 | Adult Still's disease | Dexamethasone, methylprednisolone, cyclosporin A, and tocilizumab | Lung | Blood, BAL, and pleural effusion | 16S rDNA target NGS | Meropenem, vancomycin, micafungin, imipenem-cilastatin, amikacin, cotrimoxazole, ceftriaxone, and tigecycline | Succumbed |
BAL, bronchoalveolar lavage; CNS, central nervous system; NGS, next-generation sequencing.