Table 3.
Comparison of genome sizes and amino acid identities between predicted proteins of GB09-NGR-2020, GB013-NGR-2020 and other AlphaCoV based on Sequence Demarcation Tool (SDT).
| AlphaCoV |
Genome size (Base pair) | Pairwise amino acid identity (%) |
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| GB09-NGR-2020 |
GB013-NGR-2020 |
|||||||||||
| Subgenera | Reference sequence (Accession number) | ORF1ab | S | E | M | N | ORF1ab | S | E | M | N | |
| Decacovirus | HKU10_CHN/2005 (NC_018871.1) | 28,494 | 71.37 | 64.13 | 60.91 | 74.55 | 63.33 | 71.39 | 63.43 | 60.91 | 75.29 | 63.14 |
| Duvinacovirus | HCoV-229E/2000 (NC_002645.1) | 27,317 | 68.22 | 61.73 | 63.58 | 64.36 | 61.85 | 68.28 | 60.68 | 63.58 | 64.36 | 60.92 |
| Setracovirus | HCoV-NL63/2003 (NC_005831.2) | 27,553 | 68.68 | 61.86 | 65.96 | 64.08 | 60.28 | 68.58 | 62.10 | 65.96 | 63.93 | 60.30 |
| Myotacovirus | BtMr-SAX2011 (NC_028811.1) | 27,935 | 68.63 | 62.34 | 54.54 | 63.07 | 60.62 | 68.58 | 62.63 | 54.54 | 63.52 | 60.09 |
| Minunacovirus | HKU8_HK (NC_010438.1) | 28,773 | 69.83 | 65.76 | 71.57 | 74.55 | 66.54 | 69.68 | 65.57 | 71.57 | 74.85 | 66.41 |
| Nyctacovirus | BtNv-SC2013 (NC_028833.1) | 27,783 | 69.31 | 62.86 | 56.56 | 73.69 | 62.60 | 69.38 | 63.22 | 56.56 | 73.84 | 63.68 |
| Minacovirus | FRCoV-NL/2010 (NC_030292.1) | 28,434 | 61.62 | 61.93 | 50.26 | 59.75 | 58.99 | 61.73 | 61.57 | 50.26 | 59.90 | 58.77 |
| Colacovirus | CDPHE15/USA/2006 (NC_022103.1) | 28,035 | 69.14 | 62.51 | 61.61 | 65.77 | 63.48 | 69.01 | 61.80 | 61.61 | 65.62 | 63.48 |
| Pedacovirus | PEDV/2001 (NC_003436.1) | 28,033 | 69.38 | 61.68 | 56.56 | 73.51 | 63.22 | 69.20 | 61.12 | 60.10 | 73.80 | 63.75 |
| Tegacovirus | PUR46-MAD/2000 (NC_038861.1) | 28,586 | 64.79 | 61.56 | 53.80 | 58.28 | 58.67 | 64.60 | 61.23 | 53.80 | 58.28 | 40.98 |
| Rhinacovirus | HKU2_CHN (NC_009988.1) | 27,165 | 67.83 | 60.64 | 59.48 | 65.47 | 70.19 | 67.68 | 60.71 | 59.48 | 65.77 | 70.19 |
| Luchacovirus | Lucheng-19/2013 (NC_032730.1) | 28,763 | 64.10 | 59.82 | 54.82 | 60.39 | 55.57 | 63.93 | 59.82 | 54.82 | 60.39 | 56.12 |
| Soracovirus | Shrew-CoV/Tibet2014 (KY370053) | 27,102 | 61.22 | 59.94 | 53.26 | 55.67 | 58.56 | 61.43 | 60.31 | 53.26 | 55.52 | 58.55 |
| Sunacovirus | Xingguo-74/2015 (NC_048211.1) | 25,984 | 62.23 | 60.23 | 54.16 | 58.78 | 56.98 | 64.60 | 59.38 | 54.16 | 58.93 | 56.66 |
| Unclassified AlphaCoV (This study) | GB012-NGR-2020 | 27,544 | 97.85 | 97.63 | 99.49 | 97.17 | 98.44 | 97.92 | 96.33 | 99.49 | 96.87 | 97.83 |
| Unclassified AlphaCoV | Bat143/Eswatini/2014 (OL807609) | 27,956 | 95.86 | 73.11 | 80.80 | 90.02 | 81.14 | 95.82 | 73.47 | 80.80 | 90.02 | 81.29 |
| Unclassified AlphaCoV | Bat151/Eswatini/2014 (OL807610) | 28,061 | 95.85 | 73.19 | 81.31 | 90.02 | 81.05 | 95.87 | 73.54 | 81.31 | 90.02 | 81.21 |
| Unclassified AlphaCoV | CDAB0492R (ON313747.1) | 27,989 | 96.08 | 77.07 | 96.96 | 98.36 | 96.88 | 96.12 | 76.72 | 96.96 | 98.21 | 96.96 |