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. 2022 Nov 28;3:e23. doi: 10.1017/qrd.2022.21

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© The Author(s) 2022

This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.

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Fig. 3. — Specific contacts between the E2F1-DP1 dimer and DNA. The plots show the strength of specific contacts formed by DP1 [marked with (1)] and E2F1 [marked with (2)] monomers in wild-type (WT) and methylated (ME) systems when bound alone to DNA (solo) (panel a) and together with CEBPB (complex) (panel b). Panels c and d show the strength of specific contacts by DP1and E2F1 monomers in solo- versus complex-systems in WT and ME cases, respectively. For the definition of a contact strength, see Supplementary Material.