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. 2022 Nov 28;3:e23. doi: 10.1017/qrd.2022.21

Table 1.

DNA deformation energies (kcal/mol) for the 6–35 b.p. region, calculated using a multivariate Ising model (Liebl and Zacharias, 2021)

DNA E2F1-DP1–CEBPB–DNA CEBPB–DNA E2F1-DP1–DNA
WT 120.0 ± 15.7 122.6 ± 15.7 125.5 ± 17.1 119.5 ± 15.6
(2.6 / 0.09/b.p.) (5.5 / 0.18/b.p.) (−0.50 / −0.02/b.p.)
ME 121.0 ± 15.8 132.3 ± 15.5 126.4 ± 15.4 134.5 ± 16.7
(1.0 / 0.03/b.p.) (13.3 / 0.44/b.p.) (6.4 / 0.21/b.p.) (14.5 / 0.48/b.p.)

Note: Values in the parentheses correspond to the differences in the deformation energy with respect to naked WT-DNA for the entire region and per b.p.

Abbreviations: ME, methylated; WT, wild type.