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. 2023 Jul 18;14:1231623. doi: 10.3389/fimmu.2023.1231623

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Copyright © 2023 Gordon, Capel, Guloglu, Richardson, Stafford and Deane

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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There is no correlation between the length of the CDR-H3 loop and the accessibility of the epitope surface for either Abs or sdAbs. (A) Correlation between accessibility of sdAb epitopes and length of CDR-H3 loop. (B) Correlation between accessibility of Ab epitopes and length of CDR-H3 loop.