Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Jun 3;44(29):2763–2783. doi: 10.1093/eurheartj/ehad262

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2023. Published by Oxford University Press on behalf of the European Society of Cardiology.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Mouse eosinophil-associated-ribonuclease-1 exacerbates atherogenesis and arterial calcification in apoe^−/− mice. Apoe^−/− and Apoe^−/− ΔdblGATA mice were fed with an atherosclerotic diet and administrated with recombinant mouse eosinophil-associated-ribonuclease-1 (5 μg/mouse/time) twice per week for 12 weeks. (A) Aortic root and (B) arch intima area. Scale: 500 μm. (C) Root and (D) arch α-actin⁺ smooth muscle cell contents. Scale: 200 μm. (E) Root and (F) arch Alizarin red-positive calcium deposition. Scale: 500 μm. (G) Root and (H) arch alkaline phosphatase activity-positive area. Scale: 500 μm. (I) Aortic root α-actin, osteocalcin, and nuclear Runt-related transcription factor-2 contents by immunofluorescence staining. Scale: 50 μm (top) and 25 μm (bottom). The results are expressed as mean ± standard error of mean of 10–11 (A–H) and 5 mice (I) per group.