Figure 6.

Combined incidence of abdominal aortic aneurysm (AAA) repair or mortality from AAA rupture (AAA events) in patients with diabetes prescribed metformin (purple dotted line), those with diabetes not prescribed metformin (red line), and those without diabetes (blue line). Graphs show cumulative proportion of events over 5 years for the whole cohort (A), patients with initial AAA diameter ≤ 50 mm (B), and patients with ≥6 month follow-up (C). In the whole cohort, the incidence of AAA events was less in patients with diabetes prescribed metformin than in patients who had diabetes but were not prescribed metformin (P = 0.003) or patients who did not have diabetes (P < 0.001). The incidence of AAA events was similar in people who had diabetes but were not prescribed metformin and patients who did not have diabetes (P = 0.839). Numbers at risk during different stages of follow-up are shown below the graphs. Reproduced with permission.¹⁴¹