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. 2023 Jun 20;44(29):2698–2709. doi: 10.1093/eurheartj/ehad361

Table 2.

Haematological profile and inflammatory markers of PESA participants comparing grim EAA categories

Decelerated (n = 98) Normal (n = 195) Accelerated (n = 98) P-trend
Erythrocytes 4.88 (4.64–5.18) 4.93 (4.68–5.16) 4.85 (4.64–5.137) .88
Platelet count 208.5 (186.25–24) 216 (190–252) 229 (202–261) .001
White blood cell count (num, 103/µL) 5.28 (4.48–5.99) 5.45 (4.77–6.32) 6.98 (5.42–8.35) .001
Neutrophils (num, 103/µL) 2.9 (2.52–3.36) 3.11 (2.64–3.71) 4.075 (3.09–4.97) .001
Lymphocytes (num, 103/µL) 1.66 (1.37–2.01) 1.71 (1.43–2) 1.945 (1.56–2.438) .001
Monocytes (num, 103/µL) 0.36 (0.322–0.48) 0.41 (0.35–0.5) 0.49 (0.39–0.57) .001
Eosinophils (num, 103/µL) 0.12 (0.07–0.178) 0.12 (0.08–0.2) 0.16 (0.1–0.24) .001
Basophils (num, 103/µL) 0.05 (0.04–0.06) 0.05 (0.04–0.06) 0.05 (0.05–0.08) .002
% neutrophils 56.7 (52.3–60.725) 56.5 (51.55–60.85) 59.05 (54.2–64.4) .012
% monocytes 7.35 (6.25–8.5) 7.6 (6.45–8.9) 7.1 (6–8.3) .345
% lymphocytes 32.4 (27.25–36.22) 31.3 (27.95–36.1) 28.85 (26.12–34) .006
% eosinophils 2.2 (1.4–3.2) 2.3 (1.4–3.5) 2.3 (1.6–3.175) .668
% basophils 0.9 (0.7–1.2) 0.9 (0.7–1.2) 0.9 (0.7–1.1) .216
Neutrophile/Lymphocyte 1.75 (1.45–2.28) 1.805 (1.426–2.166) 2.039 (1.61–2.48) .006
RDW 14.1 (13.62–14.8) 14.4 (13.8–14.95) 14.5 (13.92–15.08) .028
Hemoglobin 14.9 (14.3–15.6) 15 (14.3–15.6) 15.45 (14.7–15.97) .003
Hematocrit 44.15 (42.05–46.2) 44.3 (42.4–46.3) 44.7 (42.925–46.55) .1
MCV 90.55 (87.97–92.4) 90.3 (88.2–92.75) 92.1 (89.25–95.07) .003
Fibrinogen (mg/dL) 254.3 (231.45–273.32) 263.9 (238.7–284.2) 281.85 (243.15–318.92) .001
Vascular Cell Adhesion Molecule-1 641.65 (531.55–803.02) 609.7 (478.25–754.1) 621.2 (479.12–747.6) .079
P-Selectin 141.75 (109.92–163.5) 135.2 (112.4–160.9) 147.05 (111.4–177.75) .245
Oxidized low density lipoprotein 51.355 (41.35–65.98) 49.8 (41.23–61.31) 56.51 (42.52–68.325) .195
Serum lipoprotein(a) 14.4 (5.505–39.47) 19.7 (8.305–39.9) 17.25 (7.66–33.85) .809
INFLA SCORE PESA −2 (−5–1.75) −1 (−4–4) 4 (1–9) <.001
Hs C-reactive protein 0.08 (0.05–0.15) 0.11 (0.06–0.18) 0.16 (0.09–0.29) .001
FDG-PET uptakes ≥3 1 (1) 7 (3.6) 9 (9.2) .109

Data are expressed as mean mean ± SD or median (IQR) when appropriate. P-trend values are derived from Jonckheere-Terpstra tests for continuous variables and χ2 for categorical variables. Variables with statistically-significant differences are highlighted in bold.

RDW: red cell distribution width; MCV: mean corpuscular volume.