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Myeloid cell-specific FTH1 knockout mice are protected from DSS-induced colitis. A, Body weight and (B) colon length of WT and KO mice treated with high-iron diet (1000Fe, 1000mg/kg) and 2% DSS for 7 days followed by 2 days of regular water. C, H&E staining (Bar = 400 μm), (D) histological scoring, (E) TNF, (F) IL-1b and (G) F4/80 expression in DSS-treated colon tissues of WT and KO mice. *P < 0.05, **P < 0.01, n.s. not significant. Unpaired Student t test.
