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. 2023 Feb 6;29(8):1285–1296. doi: 10.1093/ibd/izad009

Figure 6.

Figure 6.

Tumors from myeloid-specific FTH1 knockout mice show reduced STAT3 activation and inflammation. A, Western analyze of p-STAT3 and (B) quantification of p-STAT3 in tumor tissues of WT and KO mice. C, Immunofluorescence staining of p-STAT3 and F4/80 in WT and KO colon tumors, quantification of p-STAT3(D) and (E) F4/80 positive cells. Quantitative PCR analysis of (F) F4/80, (G) TNF, (H) IL-1b, (I) IL-6 expression in colonic tumor tissues of WT and KO mice. *P < 0.05, **P < 0.01. Unpaired Student t test.