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. 2023 Jul 17;13:1195392. doi: 10.3389/fonc.2023.1195392

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Copyright © 2023 Pan, Wang, Hu, Xu, Jiang, Han, Chen and Liu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Pseudotime analysis for aggrephagy-mediated Myeloid cells. (A) Pseudotime analysis reveals the role of aggrephagy-related genes for Myeloid cells (3167 cells). (B) Three subgroups of Myeloid cells were obtained by re-clustering annotation based on UMAP analysis. (C) The UMAP view and clustering analysis identifying six aggrephagy-related Mac clusters. (D) Bubble map showing significantly different activity of metabolic signaling pathway among the six aggrephagy-related Mac clusters. (E) The score of the six aggrephagy-related Mac clusters in M1 type macrophages. (F) The score of the six aggrephagy-related Mac clusters in M2 type macrophages. (G) UMAP plots of the six aggrephagy-related Mac clusters in M1 type macrophages. (H) UMAP plots of the six aggrephagy-related Mac clusters in M2 type macrophages.