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APC protein expression in FAP and healthy subjects. (A) Schematic representation of the functional domains of the APC protein. (B) Localization of APC gene mutations of FAP subjects investigated here. (C) Western blots of anti-APC immunoprecipitates obtained from EBV-transformed cells from, 10 FAP and one healthy subjects. Arrows point to the full-length band. Arrowheads point to truncated APC polypeptides expressed by some FAP subjects (underlined numbers in B). #, number.
