Skip to main content
. 2023 Jul 18;14:1163466. doi: 10.3389/fimmu.2023.1163466

Figure 4.

Figure 4

Whole blood immune cell gene expression. Whole blood from pairs of sex and age matched FAP and healthy subjects (one pair per experiment) was added to TruCulture tubes with no stimulus, Candida albicans, SEB, or anti-CD3+anti-CD28 stimuli and incubated during 22 hours at 37°C. Cells and supernatants were then separated. Cells were lysed and mRNA was frozen. The 12 pairs of FAP and healthy subjects were then analyzed together by NanoString technology using a panel of 579 immune related genes listed in Supplementary Table 2 . Cells were non-stimulated (A) or received Candida albicans stimulation (B). Data were analyzed using Qlucore software. Only pairs displaying significant differences (p<0.05) are represented. Black round dots correspond to healthy subjects and red square dots correspond to FAP subjects. Whiskers represent minimum and maximum values, whereas boxes represent second and third quartiles framing the median. Each dot represents one subject. n = number of pairs. The p values (t-test) are represented as follows: **p < 0.01, *p < 0.05.