Figure 5.

Whole blood immune cell gene expression. Samples were processed as for Figure 4 . (A) SEB stimulation. (B) Anti-CD3+anti-CD28 stimulation. Data were analyzed using Qlucore software. Only pairs displaying significant differences (p<0.05) are represented. Black round dots correspond to healthy subjects and red square dots correspond to FAP subjects. Whiskers represent minimum and maximum values, whereas boxes represent second and third quartiles framing the median. Each dot represents one subject. n = number of pairs. The p values (t-test) are represented as follows: ***p < 0.001, **p < 0.01, *p < 0.05. Data of non-responders to anti-CD3 + anti-CD28 were not included in the analysis.