Table 3. Performance parameters of 99mTc-EDDA/HYNIC-TOC and 111In-DTPA-OCTREOTIDE.
| (A) Any image | (B) Liver-specific images | (C) Whole-body images | |||||||
|---|---|---|---|---|---|---|---|---|---|
| 99mTc | 111In | p | 99mTc | 111In | p | 99mTc | 111In | p | |
| Sensitivity | 93.7% (88.1 – 96.8) |
74.8% (66.6 – 81.6) |
< 0.001 | 97.8% (92.7 – 99.5) |
85.1% (76.6 – 91.0) |
< 0.001 | 77.1 (61.1 – 88.1) | 45.7% (30.4 – 61.7) | NS* |
| Specificity | 50% (15.0 – 84.9) | 50% (15.0 – 84.9) | 0.61 | 75% (41.5 – 93.4) | 75% (41.5 – 93.4) | 0.61 | 71.4 (36.4 – 92.3) | 71.4% (36.4 – 92.3) | |
| Positive LR | 1.49 (0.88 – 4.52) | 1.87 (1.11 – 5.64) | 0.75 | 3.91 (1.61 – 10.90) | 3.40 (1.4 – 10.17) | 0.84 | 2.7 (1.13 – 8.52) | 1.6 (0.62 – 5.56) | NS* |
| Negative LR | 0.50 (0.28 – 1.55) | 0.12 (0.05 – 0.42) | 0.08 | 0.02 (0.009 – 0.1) | 0.19 (0.12 – 0.42) | 0.009 | 0.32 (0.16 – 0.78) | 0.76 (0.52 – 1.61) | |
When the global Wald test was not significant, individual comparisons were not performed and thus are not presented
99mTc: 99mTc -EDDA/HYNIC-TOC; 111In: 111In -DTPA-OCTREOTIDE; LR: Likelihood Ratio; PV: Predictive Value; NS: Not Significant
Estimated sensitivities, specificities, and LRs of 99mTc-EDDA/HYNIC-TOC and 111In-DTPA-OCTREOTIDE according to disease detection in (A) Any images, (B) Liver-specific images and (C) Whole-body images