Table 1. Demographics and disease characteristics of patients with HCC.
Characteristics | Frequency | Percent | ||
---|---|---|---|---|
Total (n) | 316 | |||
Age (years) | Median (IQR) | 60 (54–67) | ||
Gender | Male | 245 | 77 | |
Female | 71 | 23 | ||
Comorbidities | None | 162 | 50 | |
Multiple | 76 | 24 | ||
Diabetes | 34 | 11 | ||
Hypertension | 34 | 11 | ||
Other | 10 | 3.2 | ||
Underlying risk factors for HCC |
Hepatitis C | 187 | 59 | |
Hepatitis B | 37 | 11 | ||
Other non-viral causes | 19 | 6 | ||
Unknown (likely non alcoholic fatty liver disease) | 78 | 24 | ||
Performance status: ECOG | 0 | 136 | 43 | |
1 | 130 | 41 | ||
2 | 36 | 11.4 | ||
3 | 13 | 4 | ||
4 | 1 | 0.6 | ||
Mode of presentation | Abdominal pain | 151 | 52 | |
Jaundice | 8 | 2.5 | ||
Weakness and weight loss | 39 | 12.34 | ||
Ascites | 59 | 18.7 | ||
Upper GI bleed | 38 | 12 | ||
Encephalopathy | 11 | 3.5 | ||
Other symptoms | 5 | 1.6 | ||
Incidental diagnosis | 20 | 7 | ||
Diagnosis on screening | 6 | 2 | ||
Laboratory values | Median platelet per cubic millimeter (Median/IQR) | 144 (91–214) | ||
Total bilirubin g/dL (Median/range) | 1 (0.6–1.7) | |||
International normalised ratio – INR (Median/range) | 1.1 (1.05–1.3) | |||
Serum albumin g/dl (Median + SD) | 3.4 (2.9 + 3.9) | |||
Alpha fetoprotein – AFP ng/mL (Median/IQR) | 42 (6–627) | |||
Radiological findings | Median tumour size in cm (IQR) (n = 281) | 5.4 (2.6–10) | ||
No. of lesions (n = 303) | 1 | 166 | 54.7 | |
2–3 | 64 | 21 | ||
>3 | 73 | 24 | ||
Underlying cirrhosis | 270 | 85.4 | ||
Extrahepatic involvement of HCC | 39 | 12.3 | ||
Presence of PVT | 98 | 31 | ||
Child–Pugh class | A | 216 | 68.4 | |
B | 76 | 24 | ||
C | 24 | 7.6 | ||
MELD score | 6–16 | 289 | 91.4 | |
17–40 | 21 | 6.6 | ||
BCLC staging | 0 | 17 | 5.4 | |
A | 91 | 28.8 | ||
B | 64 | 20.3 | ||
C | 123 | 39 | ||
D | 10 | 3.2 |