Table 6.

Urine electrolytes during the ML418 infusion protocol

	0.4% NaCl		Infusion + 14 Days of 8% NaCl
	Vehicle	ML418	Vehicle	ML418
K+/creatinine	14.7 ± 0.7	13.7 ± 0.9	15.8 ± 0.3	18.3 ± 0.7
Na+/creatinine	33 ± 2	35 ± 4	197 ± 54	333 ± 21*
Ca2+/creatinine	0.45 ± 0.07	0.56 ± 0.12	1.41 ± 0.28	2.60 ± 0.21*
Cl−/creatinine	40 ± 2	41 ± 4	190 ± 50	314 ± 17*
Creatinine, mM	9.38 ± 0.72	8.42 ± 0.65	2.05 ± 0.91	0.95 ± 0.08

*Statistical significance.