Table 2.
Pearson correlation reveals skeletal muscle mass is positively associated with CHO oxidation in FOLFOX chemotherapy treated mice
| Relative V̇o2, mL/kg BW/h |
Energy Expenditure, kcal/kg BW/h |
CHO Oxidation, g/min |
Lipid Oxidation, g/min |
|||||
|---|---|---|---|---|---|---|---|---|
| PBS | FOLFOX | PBS | FOLFOX | PBS | FOLFOX | PBS | FOLFOX | |
| Hindlimb muscle mass, mg | 0.296 | −0.088 | 0.294 | 0.025 | −0.049 | 0.867* | 0.383 | 0.452 |
| Body fat % | −0.675 | −0.855* | −0.644 | −0.869* | −0.117 | −0.277 | −0.612 | −0.471 |
| Fasting glucose, mg/dL | 0.694 | 0.437 | 0.670 | 0.392 | 0.522 | −0.043 | 0.200 | 0.559 |
| Fasting insulin, ng/mL | −0.013 | 0.293 | −0.091 | 0.337 | −0.153 | 0.546 | 0.395 | −0.092 |
Pearson correlation coefficients for associations between daily average oxygen consumption (V̇o2), energy expenditure (EE), carbohydrate (CHO), and lipid oxidation in the four cycle PBS- or FOLFOX-treated mice (n = 8/group). Values are Pearson r coefficients. Statistical significance is set to P < 0.05. bold with * denotes significant P value. BW, body weight; dL, deciliter; FOLFOX, 5-fluorouracil, leucovorin, oxaliplatin; g, grams; kcal, kilocalories; kg, kilograms; mg, milligrams; min, minutes; ng, nanograms.